Application of Aptamer-based Biosensors in Early Diagnosis of Gastric Cancer: A Promising Method for Early Detection

Personalized medicine is a relatively new approach that addresses differences between patients based on unique features such as genetic make-up, environment, and physiology. Aptamers are synthetic sequences of single-stranded DNA or RNA with particular three-dimensional conformation binds to target. Aptamer-based biosensors promising tools detect disease markers, especially in cancer. Gastric cancer the third most common cause cancer-related deaths worldwide has very high prevalence Asia. Currently, there lack effective screening for early detection gastric Thus, identifying methods markers crucial. In this study, role aptamer-based biomarkers diagnosis reviewed.